Interconnection between liver enzymes & Hba1C to lipid profile

Interconnection between liver enzymes & Hba1C to lipid profile

Many previous studies have linked both DM, especially T2DM as well as altered liver function to CVD.Uncontrolled DM is said to affect cardiac function. This study was undertaken on non hospitalised T2DM patients (both males and females) to find out if liver enzymes and HbA1c are associated to cardiac function by linking their associations
to individual lipid profile tests.In all patients comprising of a total of 50, significant associations of both negative and positive were observed between each liver enzyme and HbA1c analyte studied to individual lipid profile tests at a p value ranging from <0.05 to < 0.001 justifying that both liver and DM are associated to cardiac function.

While γ-GT and HbA1c showed associations to TC, TGs and VLDL-c in the case of males, females showed associations to all analytes compared to all lipid profile parameters at p ranging
from <0.08 to <0.01.The outcome the results in this study strongly recommends that to assess cardiac functions in T2DM patients, along with lipid profile, the clinicians should occasionally recommend HbA1c as well as liver enzymes as additional package tests. More studies are needed in this field to arrive at a consensus package tests related to both DM and liver function to do occasionally in all T2DM patients attending Cardiology
clinics.